Assistant Professor, Biological Sciences
B.Sc., M.Sc., PGDCR, Ph.D.
Microbiology, Cell Biology, Immunology, Pharmacology
Dr. Brijesh has been working with School of Science from June 2011. Previously, he has worked at the Foundation for Medical Research (FMR), Mumbai, as a Post-Doctoral Fellow. His responsibilities were to format initiatives and design processes towards down-streaming the potential of the guava leaf extract as an anti-diarrhoeal into a standardized product.
1. Currently his work involves evaluating the mechanism of action of medicinal plants with anxiolytic and anti-depressant activities using animal models and gene expression studies and identifying the molecule for observed activities using molecular docking studies.
2. Another aspect of his current research activities is to evaluate nano-drug delivery systems such as solid lipid nanoparticles (SLN), niosomes, nano-structures lipid carries (NLC) and nanoemulsions for delivery of combination of drugs used in treatment of rheumatoid arthritis and psoriasis. The focus, on one hand, has been on synthesising SLNs and encapsulation of anti-rheumatic drugs using a Quality by Design (QbD) approach for oral delivery. On the other hand, niosomes NLCs and nanomulsions are being explored for their potential for topical delivery of anti-rheumatic and anti-psoriatic drugs
- Teaching Biochemistry, Bioanalytical Chemistry, Biostatistics, Cell Biology, Immunology, Microbiology, and Pharmacology to U.G., P.G. and Ph.D. students of the Biomedical Science and Biological Sciences courses.
- Guiding research work of Ph. D. students. Completed: 3; Ongoing: 5
- Associate Editor at the Biomedical Research Journal (BRJ).
- Program Chair-person of the “5-Year Integrated M.Sc. in Biomedical Science” program.
- Member Secretary: 1) BOS of the “5-Year Integrated M.Sc. in Biomedical Science” program. 2) SVKM’s Institutional Ethics Committee (IEC)
- In-charge of the Students’ Disciplinary Committee, SDSOS Library.
Life member of Mumbai Immunology Group
Life member of Indian Science Congress Association
1. Sahoo S, Brijesh S. Pharmacogenomic assessment of herbal drugs in affective disorders. Biomedicine and Pharmacotherapy 2019. 109: 1148–1162.
2. Parmar A, Brijesh S. Niosomes as Transdermal Drug Delivery System. Biomedical Research Journal. 2018. 5(2): 54–63.
3. Martins J, Brijesh S. Phytochemistry and pharmacology of anti-depressant medicinal plants: A review. Biomedicine & Pharmacotherapy. 2018. 104: 343–365.
4. Thakkar M, Brijesh S. Stability-indicating HPLC method for primaquine diphosphate: An application to niosomal formulation. Biomedical Research Journal. 2018.
5(1), 39–51 5. Thakkar M, Brijesh S. Physicochemical investigation and in vivo activity of anti-malarial drugs co-loaded in Tween 80 niosomes. Journal of Liposome Research. 2018. 28(4): 315–321.
6. Kargutkar S, Brijesh S. Anti-inflammatory evaluation and characterization of leaf extract of Ananas comosus. Inflammopharmacology. 2017. 26(2): 469–477.
7. Thakkar M, Brijesh S. Opportunities and challenges for niosomes as drug delivery systems. Current Drug Delivery 2016. 13(8): 1275–1289.
8. Kargutkar S, Brijesh S. Anti-rheumatic activity of Ananas comosus fruit peel extract in a complete Freund’s adjuvant rat model. Pharmaceutical Biology 2016; 54 (11), 2616–2622.
9. Thakkar M, Brijesh S. Combating malaria with nanotechnology-based targeted and combinatorial drug delivery strategies. Drug Delivery and Translational Research. 2016. 6 (4): 414–425.
10. Mishra R, Pandit K, Bhagwat AM, Brijesh S. Antihyperlipidemic activity of alcoholic extracts of Trichosanthes anguina in Triton WR 1339 induced hyperlipidemic rats. International Journal of Pharmaceutical Sciences and Research. 2014. 5(10): 4269–4274.
11. Pandit K, Mishra R, Brijesh S, Bhagwat A, Bhatt P. Lipid lowering activity of Feronia limonia leaf in Triton WR-1339 (Tyloxapol) induced hyperlipidemic rats. International Journal of Pharmacy and Pharmaceutical Sciences. 2014. 6(8): 156–158.
12. Birdi TJ, Brijesh S, Daswani PG. Bactericidal effect of selected antidiarrhoeal medicinal plants on intracellular heat-stable enterotoxin-producing Escherichia coli. Indian Journal of Pharmaceutical Sciences. 2014. 76(3): 229–235.
13. PG Daswani, AA Ghadge, S Brijesh, TJ Birdi. Preparation of decoction of medicinal plants: a self-help measure? The Journal of Alternative and Complementary Medicine. 2011. 17(12): 1099–1100
14. Brijesh S, Tetali P, Antia N, Birdi T. 2011. Study on effect of anti-diarrhoeal medicinal plants on enteropathogenic Escherichia coli induced interleukin-8 secretion by intestinal epithelial cells. Alternative Medicine Studies. 1:e16: 64–69
15. Birdi TJ, Daswani PG, Brijesh S, Tetali P. In vitro antigiardial and antirotaviral activity of Psidium guajava L. leaves. Indian Journal of Pharmacology. 2011. 43(5): 616–617.
16. Daswani PG, Brijesh S, Tetali P, Birdi TJ. 2011. Studies on the activity of Cyperus rotundus Linn. tubers against infectious diarrhea. Indian Journal Pharmacology. 43(3): 340–344
17. Birdi T, Daswani P, Brijesh S, Tatali P, Antia N, Natu A. 2010. Newer insights into the mechanism of action of Psidium guajava L. leaves in infectious diarrhoea. BiomedCentral Complementary and Alternative Medicine. 10:33
18. Daswani PG, Brijesh S, Tetali P, Antia NH, Birdi TJ. 2010. Studies on Antidiarrhoeal Activity of Zingiber officinale (Rosc.). Current Science. 98 (2): 222–229
19. Brijesh S, Daswani P, Tetali P, Antia N, Birdi T. 2009. Studies on the antidiarrhoeal activity of Aegle marmelos unripe fruit: Validating its traditional usage. BiomedCentral Complementary and Alternative Medicine. 9:47
20. Brijesh S, Daswani PG, Tetali P, Rojatkar SR, Antia NH, Birdi TJ. 2006. Studies on Pongamia pinnata (L.) Pierre leaves: Understanding the mechanism(s) of action in infectious diarrhea. Journal of Zhejiang University SCIENCE B. 7: 665–674.
21. Brijesh S, Daswani PG, Tetali P, Antia NH. Birdi TJ. 2006. Studies on Dalbergia sissoo (Roxb.) leaves: Possible mechanism(s) of action in infectious diarrhoea. Indian Journal of Pharmacology. 38: 120–124
In Worshop/Conference Proceedings